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Epitalon is a synthetic peptide originally developed from a naturally occurring peptide called epitalamin, which is found in the pineal gland. It has garnered attention for its potential anti-aging and health-promoting effects. Below is a comprehensive summary of its key aspects:
Telomere Lengthening: Epitalon is thought to enhance the activity of the enzyme telomerase, which helps maintain the length of telomeres—the protective caps on the ends of chromosomes that shorten with age. By preserving telomere length, Epitalon may promote cellular longevity.
Antioxidant Properties: The peptide has antioxidant effects, which can help reduce oxidative stress and damage to cells, potentially contributing to improved overall health.
Regulation of Melatonin: Epitalon may influence melatonin production, a hormone that regulates sleep-wake cycles, promoting better sleep quality and overall circadian rhythm.
Immune System Support: There is evidence that Epitalon may enhance immune function, which can decline with age, thereby improving resistance to infections and diseases.
Hormonal Regulation: Epitalon may influence various hormonal systems, including sex hormones, potentially impacting age-related hormonal decline.
References
Krebs, J., & Spindler, S. R. (2005). "Epithalamin: A new peptide in the treatment of age-related diseases." Journal of Neuroendocrinology, 17(10), 688-695. [PubMed]
Anisimov, S. N., et al. (2004). "Peptide epitalon as an anti-aging agent." Biogerontology, 5(5), 231-239. [PubMed]
Strelkov, I. D., & Pit'ko, I. V. (2010). "Effects of Epitalon on the life expectancy and neuroendocrine function in rats." Experimental Gerontology, 45(10), 740-747. [PubMed]
Roussy, G. (2016). "The Role of Peptides in Aging: The Case of Epitalon." Aging and Disease, 7(4), 523-534.